الرئيسيةعريقبحث

أعراض انسحابية

الأعراض الانسحابية (Withdrawal)‏ هي مجموعة من الأعراض التي تصيب الأنسان عند إقلاعه عن مواد كحولية، أو أدوية مخدرة، أو مخدرات.[5][6][7]

أعراض انسحابية
معلومات عامة
الاختصاص طب نفسي،  وعلم النفس 
فهرس الإدمان والاعتمادية[1][2][3][4]

لكي يشعر المرء بالأعراض الانسحابية، عليه أن يكون يعتمد جسديا أو نفسيا (أو كلاهما) على تعاطي المواد (غالبا ما يشار إليه بالاعتماد على الكيمياويات).

وهي مجموعة من الأعراض الفزيولوجية خاصة التي تصيب الشخص المدمن على مادة مخدرة.

مراجع

  1. Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 15: Reinforcement and Addictive Disorders". In Sydor A, Brown RY (المحررون). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (الطبعة 2nd). New York: McGraw-Hill Medical. صفحات 364–375.  .
  2. Nestler EJ (December 2013). "Cellular basis of memory for addiction". Dialogues Clin. Neurosci. 15 (4): 431–443. PMC . PMID 24459410. Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that drive the compulsive seeking and taking of drugs, and loss of control over drug use, that define a state of addiction. ... A large body of literature has demonstrated that such ΔFosB induction in D1-type [nucleus accumbens] neurons increases an animal's sensitivity to drug as well as natural rewards and promotes drug self-administration, presumably through a process of positive reinforcement ... Another ΔFosB target is cFos: as ΔFosB accumulates with repeated drug exposure it represses c-Fos and contributes to the molecular switch whereby ΔFosB is selectively induced in the chronic drug-treated state.41. ... Moreover, there is increasing evidence that, despite a range of genetic risks for addiction across the population, exposure to sufficiently high doses of a drug for long periods of time can transform someone who has relatively lower genetic loading into an addict.
  3. "Glossary of Terms". Mount Sinai School of Medicine. Department of Neuroscience09 فبراير 2015.
  4. Volkow ND, Koob GF, McLellan AT (January 2016). "Neurobiologic Advances from the Brain Disease Model of Addiction". N. Engl. J. Med. 374 (4): 363–371. doi:10.1056/NEJMra1511480. PMID 26816013. Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) referring to recurrent use of alcohol or other drugs that causes clinically and functionally significant impairment, such as health problems, disability, and failure to meet major responsibilities at work, school, or home. Depending on the level of severity, this disorder is classified as mild, moderate, or severe.
    Addiction: A term used to indicate the most severe, chronic stage of substance-use disorder, in which there is a substantial loss of self-control, as indicated by compulsive drug taking despite the desire to stop taking the drug. In the DSM-5, the term addiction is synonymous with the classification of severe substance-use disorder.
  5. Alexander, GC; Sayla MA; Holmes HM; Sachs GA (11 April 2006). "Prioritizing and stopping prescription medicines". Canadian Medical Association Journal. 174 (8): 1083–1084. doi:10.1503/cmaj.050837. PMC . PMID 16606954. مؤرشف من الأصل في 15 يونيو 201811 نوفمبر 2011.
  6. Peter Lehmann, المحرر (2002). Coming off Psychiatric Drugs. Germany: Peter Lehmann Publishing.  . مؤرشف من الأصل في 28 مايو 2019.
  7. Drogues : des associations réclament des seringues en prison - تصفح: نسخة محفوظة 02 فبراير 2018 على موقع واي باك مشين.

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