إنترلوكين-10 (Interleukin 10) ويُدعى اختصارًا IL-10، هو سيتوكين مُضاد للالتهاب. يُشفر بجين IL10 في الإنسان.[1]
Interleukin 10 | |||||||
---|---|---|---|---|---|---|---|
المعرفات | |||||||
الأسماء المستعارة | CSIF, interleukin-10, T-cell growth inhibitory factor, IL10, cytokine synthesis inhibitory factor | ||||||
معرفات خارجية | |||||||
أورثولوج | |||||||
الأنواع | الإنسان | الفأر | |||||
أنتريه | n/a | ||||||
Ensembl | n/a | n/a | |||||
يونيبروت |
|
| |||||
RefSeq (مرسال ر.ن.ا.) |
|
| |||||
RefSeq (بروتين) |
|
| |||||
الموقع (UCSC | n/a | ||||||
بحث ببمد | n/a | ||||||
ويكي بيانات | |||||||
المراجع
- Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence". Immunogenetics. 46 (2): 120–8. doi:10.1007/s002510050250. PMID 9162098.
قراءات أخرى
- Bortesi L, Rossato M, Schuster F, Raven N, Stadlmann J, Avesani L, Falorni A, Bazzoni F, Bock R, Schillberg S, Pezzotti M (March 2009). "Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco". BMC Biotechnology. 9 (1): 22. doi:10.1186/1472-6750-9-22. PMC . PMID 19298643.
- Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annual Review of Immunology. 19 (1): 683–765. doi:10.1146/annurev.immunol.19.1.683. PMID 11244051.
- Girndt M (2003). "Humoral immune responses in uremia and the role of IL-10". Blood Purification. 20 (5): 485–8. doi:10.1159/000063553. PMID 12207099.
- Beebe AM, Cua DJ, de Waal Malefyt R (2003). "The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS)". Cytokine & Growth Factor Reviews. 13 (4–5): 403–12. doi:10.1016/S1359-6101(02)00025-4. PMID 12220553.
- Mocellin S, Panelli MC, Wang E, Nagorsen D, Marincola FM (January 2003). "The dual role of IL-10". Trends in Immunology. 24 (1): 36–43. doi:10.1016/S1471-4906(02)00009-1. PMID 12495723.
- Roncarolo MG, Battaglia M, Gregori S (June 2003). "The role of interleukin 10 in the control of autoimmunity". Journal of Autoimmunity. 20 (4): 269–72. doi:10.1016/S0896-8411(03)00047-7. PMID 12791310.
- Groux H, Cottrez F (June 2003). "The complex role of interleukin-10 in autoimmunity". Journal of Autoimmunity. 20 (4): 281–5. doi:10.1016/S0896-8411(03)00044-1. PMID 12791313.
- Llorente L, Richaud-Patin Y (June 2003). "The role of interleukin-10 in systemic lupus erythematosus". Journal of Autoimmunity. 20 (4): 287–9. doi:10.1016/S0896-8411(03)00043-X. PMID 12791314.
- Asadullah K, Sabat R, Friedrich M, Volk HD, Sterry W (June 2004). "Interleukin-10: an important immunoregulatory cytokine with major impact on psoriasis". Current Drug Targets. Inflammation and Allergy. 3 (2): 185–92. doi:10.2174/1568010043343886. PMID 15180472.
- Stenvinkel P, Ketteler M, Johnson RJ, Lindholm B, Pecoits-Filho R, Riella M, Heimbürger O, Cederholm T, Girndt M (April 2005). "IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly". Kidney International. 67 (4): 1216–33. doi:10.1111/j.1523-1755.2005.00200.x. PMID 15780075.
- Chang CF, Wan J, Li Q, Renfroe SC, Heller NM, Wang J (July 2017). "Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage". Neurobiol. Dis. 103: 54–69. doi:10.1016/j.nbd.2017.03.016. PMC . PMID 28365213.
- Copeland KF (December 2005). "Modulation of HIV-1 transcription by cytokines and chemokines". Mini Reviews in Medicinal Chemistry. 5 (12): 1093–101. doi:10.2174/138955705774933383. PMID 16375755.
روابط خارجية
- Interleukin-10 في المَكتبة الوَطنية الأمريكية للطب نظام فهرسة المواضيع الطبية (MeSH).