| رقم أو اسم عامل التخثر |
الوضيفة
|
|---|
| I (فيبرينوجين) |
أشكال تجلط (الليفين)
|
| II (بروثرومبين) |
Its active form (IIa) activates I, V, VII, XIII, protein C, platelets
|
| ثرومبوبلاستين |
Co-factor of VIIa (formerly known as factor III)
|
| كالسيوم |
Required for coagulation factors to bind to phospholipid (formerly known as factor IV)
|
| V (proaccelerin, labile factor) |
Co-factor of X with which it forms the prothrombinase complex
|
| VI |
Unassigned – old name of Factor Va
|
| VII (stable factor) |
Activates IX, X
|
| VIII (antihemophilic factor) |
Co-factor of IX with which it forms the tenase complex
|
| IX (Christmas factor) |
Activates X: forms tenase complex with factor VIII
|
| X (Stuart-Prower factor) |
Activates II: froms prothrombinase complex with factor V
|
| XI (plasma thromboplastin antecedent) |
Activates XII, IX and prekallikrein
|
| XII (Hageman factor) |
Activates prekallikrein and انحلال الفبرين
|
| XIII (fibrin-stabilizing factor) |
Crosslinks fibrin
|
| عامل فون ويليبراند |
Binds to VIII, mediates platelet adhesion
|
| prekallikrein |
Activates XII and prekallikrein; cleaves HMWK
|
| high molecular weight kininogen (HMWK) |
Supports reciprocal activation of XII, XI, and prekallikrein
|
| فايبرونيكتين |
Mediates cell adhesion
|
| ضد الثرومبين III |
Inhibits IIa, Xa, and other proteases;
|
| heparin cofactor II |
Inhibits IIa, cofactor for heparin and dermatan sulfate ("minor antithrombin")
|
| بروتين C |
Inactivates Va and VIIIa
|
| بروتين S |
Cofactor for activated protein C (APC, inactive when bound to C4b-binding protein)
|
| بروتين Z |
Mediates thrombin adhesion to phospholipids and stimulates degradation of factor X by ZPI
|
| Protein Z-related protease inhibitor (ZPI) |
Degrades factors X (in presence of protein Z) and XI (independently)
|
| plasminogen |
Converts to plasmin, lyses fibrin and other proteins
|
| alpha 2-antiplasmin |
Inhibits plasmin
|
| منشط بلازمينوجين النسيجي (tPA) |
Activates plasminogen
|
| يوروكيناز |
Activates plasminogen
|
| plasminogen activator inhibitor-1 (PAI1) |
Inactivates tPA & urokinase (endothelial PAI)
|
| plasminogen activator inhibitor-2 (PAI2) |
Inactivates tPA & urokinase (مشيميl PAI)
|
| cancer procoagulant |
Pathological العامل العاشر activator linked to thrombosis in سرطان
|
