ألبيومين المصل البشري هو نسخة من ألبيومين المصل توجد في دم الإنسان.[1][2][3] وهو أكثر بروتين وفرة في بلازما الدم إذ يشكل ما يقارب من نصف بروتينات المصل .
| ألبيومين المصل | |
|---|---|
 PDB rendering based on 1e7h.
| |
| المعرفات | |
| الرمز | ALB |
| رمز ATC | B05AA01 |
| CAS | 9006-53-5 |
| أنتريه | 213 |
| HUGO | 399 |
| أوميم | 103600 |
| بنك بيانات البروتين | 1E7H |
| RefSeq | NM_000477 |
| يونيبروت | P02768 |
| بيانات أخرى | |
| الموقع الكروموسومي | Chr. 4 q13.3 |
قراءة إضافية
- Komatsu T, Nakagawa A, Curry S, Tsuchida E, Murata K, Nakamura N, Ohno H (2009). "The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O(2) and CO binding to iron protoporphyrin IX". Org. Biomol. Chem. 7 (18): 3836–41. doi:10.1039/b909794e. PMID 19707690.
- Milojevic J, Raditsis A, Melacini G (2009). "Human Serum Albumin Inhibits Aβ Fibrillization through a "Monomer-Competitor" Mechanism". Biophys. J. 97 (9): 2585–94. doi:10.1016/j.bpj.2009.08.028. PMC . PMID 19883602.
- Silva AM, Hider RC (2009). "Influence of non-enzymatic post-translation modifications on the ability of human serum albumin to bind iron. Implications for non-transferrin-bound iron speciation". Biochim. Biophys. Acta. 1794 (10): 1449–58. doi:10.1016/j.bbapap.2009.06.003. PMID 19505594.
- Otosu T, Nishimoto E, Yamashita S (2010). "Multiple conformational state of human serum albumin around single tryptophan residue at various pH revealed by time-resolved fluorescence spectroscopy". J. Biochem. 147 (2): 191–200. doi:10.1093/jb/mvp175. PMID 19884191.
- Blindauer CA, Harvey I, Bunyan KE, Stewart AJ, Sleep D, Harrison DJ, Berezenko S, Sadler PJ (2009). "Structure, Properties, and Engineering of the Major Zinc Binding Site on Human Albumin". J. Biol. Chem. 284 (34): 23116–24. doi:10.1074/jbc.M109.003459. PMC . PMID 19520864.
- Juárez J, López SG, Cambón A, Taboada P, Mosquera V (2009). "Influence of electrostatic interactions on the fibrillation process of human serum albumin". J Phys Chem B. 113 (30): 10521–9. doi:10.1021/jp902224d. PMID 19572666.
- Fu BL, Guo ZJ, Tian JW, Liu ZQ, Cao W (2009). "[Advanced glycation end products induce expression of PAI-1 in cultured human proximal tubular epithelial cells through NADPH oxidase dependent pathway]". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 25 (8): 674–7. PMID 19664386.
- Ascenzi P, di Masi A, Coletta M, Ciaccio C, Fanali G, Nicoletti FP, Smulevich G, Fasano M (2009). "Ibuprofen Impairs Allosterically Peroxynitrite Isomerization by Ferric Human Serum Heme-Albumin". J. Biol. Chem. 284 (45): 31006–17. doi:10.1074/jbc.M109.010736. PMC . PMID 19734142.
- Sowa ME, Bennett EJ, Gygi SP, Harper JW (2009). "Defining the Human Deubiquitinating Enzyme Interaction Landscape". Cell. 138 (2): 389–403. doi:10.1016/j.cell.2009.04.042. PMC . PMID 19615732.
- Curry S (2002). "Beyond expansion: structural studies on the transport roles of human serum albumin". Vox Sang. 83 Suppl 1: 315–9. doi:10.1111/j.1423-0410.2002.tb05326.x. PMID 12617161.
- Guo S, Shi X, Yang F, Chen L, Meehan EJ, Bian C, Huang M (2009). "Structural basis of transport of lysophospholipids by human serum albumin". Biochem. J. 423 (1): 23–30. doi:10.1042/BJ20090913. PMID 19601929.
- de Jong PE, Gansevoort RT (2009). "Focus on microalbuminuria to improve cardiac and renal protection". Nephron Clin Pract. 111 (3): c204–10, discussion c211. doi:10.1159/000201568. PMID 19212124.
- Page TA, Kraut ND, Page PM, Baker GA, Bright FV (2009). "Dynamics of loop 1 of domain I in human serum albumin when dissolved in ionic liquids". J Phys Chem B. 113 (38): 12825–30. doi:10.1021/jp904475v. PMID 19711930.
- Roche M, Rondeau P, Singh NR, Tarnus E, Bourdon E (2008). "The antioxidant properties of serum albumin". FEBS Lett. 582 (13): 1783–7. doi:10.1016/j.febslet.2008.04.057. PMID 18474236.
- Wyatt AR, Wilson MR (2010). "Identification of Human Plasma Proteins as Major Clients for the Extracellular Chaperone Clusterin". J. Biol. Chem. 285 (6): 3532–9. doi:10.1074/jbc.M109.079566. PMC . PMID 19996109.
- Cui FL, Yan YH, Zhang QZ, Qu GR, Du J, Yao XJ (2010). "A study on the interaction between 5-Methyluridine and human serum albumin using fluorescence quenching method and molecular modeling". J Mol Model. 16 (2): 255–62. doi:10.1007/s00894-009-0548-4. PMID 19588173.
- Caridi G, Dagnino M, Simundic AM, Miler M, Stancic V, Campagnoli M, Galliano M, Minchiotti L (2010). "Albumin Benkovac (c.1175 A > G; p.Glu392Gly): a novel genetic variant of human serum albumin". Translational Research. 155 (3): 118–9. doi:10.1016/j.trsl.2009.10.001. PMID 20171595.
- Deeb O, Rosales-Hernández MC, Gómez-Castro C, Garduño-Juárez R, Correa-Basurto J (2010). "Exploration of human serum albumin binding sites by docking and molecular dynamics flexible ligand-protein interactions". Biopolymers. 93 (2): 161–70. doi:10.1002/bip.21314. PMID 19785033.
- Karahan SC, Koramaz I, Altun G, Uçar U, Topbaş M, Menteşe A, Kopuz M (2010). "Ischemia-modified albumin reduction after coronary bypass surgery is associated with the cardioprotective efficacy of cold-blood cardioplegia enriched with N-acetylcysteine: a preliminary study". Eur Surg Res. 44 (1): 30–6. doi:10.1159/000262324. PMID 19955769.
- Jin C, Lu L, Zhang RY, Zhang Q, Ding FH, Chen QJ, Shen WF (2009). "Association of serum glycated albumin, C-reactive protein and ICAM-1 levels with diffuse coronary artery disease in patients with type 2 diabetes mellitus". Clin. Chim. Acta. 408 (1–2): 45–9. doi:10.1016/j.cca.2009.07.003. PMID 19615354.
روابط خارجية
- Human Albumin structure in the بنك بيانات البروتينات
- Human Albumin information in the Swis-Prot/TrEMBL database
- Human Serum Albumin on the Human Protein Reference Database
- Albumin binding prediction
- Albumin at Lab Tests Online
- Albumin: analyte monograph from the Association for Clinical Biochemistry and Laboratory Medicine
مراجع
- Human albumin solution for resuscitation and volume expansion in critically ill patients" Cochrane Database of Systematic Reviews 2004, Issue 4. Art. No.: CD001208. doi:10.1002/14651858.CD001208.pub2. نسخة محفوظة 14 ديسمبر 2017 على موقع واي باك مشين.
- Mohamadi-Nejada A, Moosavi-Movahedi AA, Safariana S, Naderi-Maneshc MH, Ranjbarc B, Farzamid B, Mostafavie H, Larijanif MB, Hakimelahi GH, A (July 2002). "The thermal analysis of nonezymatic glycosylation of human serum albumin: differential scanning calorimetry and circular dichroism studies". Thermochimica Acta. 389 (1–2): 141–151. doi:10.1016/S0040-6031(02)00006-0.
- Green P, Woglom AE, Genereux P, Daneault B, Paradis JM, Schnell S, Hawkey M, Maurer MS, Kirtane AJ, Kodali S, Moses JW, Leon MB, Smith CR, Williams M (2012). "The impact of frailty status on survival after transcatheter aortic valve replacement in older adults with severe aortic stenosis: a single-center experience". JACC Cardiovascular Interventions. 5 (9): 974–981. doi:10.1016/j.jcin.2012.06.011. PMC . PMID 22995885. مؤرشف من الأصل في 24 سبتمبر 2015.